TELMISARTAN-D3

TELMISARTAN-D3 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Telmisartan-d₃ is intended for use as an internal standard for the quantification of telmisartan by GC- or LC-MS. Telmisartan is a nonpeptide angiotensin (AT) II receptor antagonist which selectively and insurmountably inhibits the AT II receptor subtype AT₁ (K_i = 3.7 nM). It also acts as a partial agonist of peroxisome proliferator-activated receptor gamma (PPARγ), activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (; EC₅₀ = 4.5 μM). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.

• Chemische Eigenschaften

  Off-White Crystalline Solid

• Verwenden

  Labelled Telmisartan, an angiotensin II receptor antagonist

• Verwenden

  TelMisartan-d3 can be intended for use as an internal standard for the quantification of Telmisartan by GC- or LC-mass spectrometry.

• Verwenden

  TelMisartan-d3 is an angiotensin II receptor antagonist.

TELMISARTAN-D3 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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