17-(2-Propenyl)morphinan-3-ol

levallorphan Chemische Eigenschaften,Einsatz,Produktion Methoden

• Definition

  ChEBI: Levallorphan is a morphinane alkaloid.

• Trademarks

  Lorfan (Roche).

• Clinical Use

  Levallorphan is an opioid antagonist with practically no analgesic action. It has been used as one of the first relative pure antagonists for the treatment of opioid overdosage, to reverse opioid central depression and to antagonize opioidinduced respiratory impairment . The compound is now replaced by naloxone .

• Synthese

  Starting material for the levallorphan synthesis is 1-(4-methoxybenzyl)- 1,2,3,4,5,6,7,8-octahydro isoquinoline (1) .
  

• läuterung methode

  It crystallises from aqueous EtOH. It is a narcotic antagonist. [Schneider & Grüssner Helv Chim Acta 34 2211 1951, Hellerbach Helv Chim Acta 39 429 1956.]

17-(2-Propenyl)morphinan-3-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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