Fenalamid

fenalamide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Fenalamide,ZYF Pharm Chemical

• Verwenden

  Relaxant (smooth muscle).

• Definition

  ChEBI: Fenalamide is a member of acetamides.

• Manufacturing Process

  To a solution of 25.5 g of phenylethylmalonic acid ethyl ester chloride in 100 ml of anhydrous benzene 5.3 g of anhydrous sodium carbonate are added followed by 11.6 g of N,N-diethylethylenediamine in small portion. After the spontaneous heat evolution has subsided the mixture is refluxed for 2 hours until the evolution of carbon dioxide ceases. After cooling the mixture is allowed to stand for some hours, the precipitated sodium chloride is removed by filtration. The filtrat is evaporated to dryness in vacuo and the residue distilled at 182-188°C/3 mm Hg.
  The phenylethylmalonic acid (diethyl amino) ethylamide ethyl ester (free base) is converted in hydrochloride by bubbling hydrogen chloride into a diethyl ether solution of the free base; melting point 71-74°C.

• Therapeutic Function

  Spasmolytic, Smooth muscle relaxant

fenalamide Upstream-Materialien And Downstream Produkte

Fenalamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(2)Suppliers

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