Ximoprofen

ximoprofen Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Ximoprofen,Logeais

• Definition

  ChEBI: A monocarboxylic acid that is 2-phenylpropionic acid in which the phenyl group is substituted at the para position by a 3-(hydroxyimino)cyclohexyl group.

• Manufacturing Process

  2-[4-(3'-Oxocyclohexyl)phenyl]propionic acid (4.0 g; 16.2 mmoles) is dissolved in 1 N sodium hydroxide (55 ml) and treated with hydroxylamine hydrochloride (2.22 g; 32 mmoles) during 24 h at room temperature. The gummy precipitate formed on acidification is converted to the sodium salt in aqueous solution which is then evaporated to dryness. The residue is dissolved in methanol or ethanol to remove an insoluble. After evaporating off the alcool, the sodium salt is again dissolved in water and converted to the acid which is crystallized from water-methanol (1:1), to give 3.0 g (yield 70%) of 2-[4-(3'-hydroxyimino-cyclohexyl)phenyl]propionic acid, melting point 178°C.

• Therapeutic Function

  Antiinflammatory

ximoprofen Upstream-Materialien And Downstream Produkte

Ximoprofen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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