D-manno-2-Heptulose

D-MANNOHEPTULOSE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  D-Glucose is phosphorylated by glucokinase and three tissue-specific hexokinases to produce glucose-6-phosphate in humans. D-Mannoheptulose is a heptose that inhibits glucokinases and hexokinases from diverse organisms through competition with D-glucose (K_i = 0.25 mM). It blocks glucose oxidation and glucose-mediated insulin release from pancreatic islet cells. D-Mannoheptulose prevents the conversion of glucose to glucose-6-phosphate that can mediate the activation of the carbohydrate response element binding protein. By blocking glucose phosphorylation, D-mannoheptulose causes transient hyperglycemia in dogs when given at 1 g/kg but not at 8 mg/kg, although postprandial energy expenditure is increased at the lower dose.

• Chemische Eigenschaften

  White Solid

• Verwenden

  Mannoheptulose occurs naturally in avocado fruit. It is used for normalizing insulin levels and reducing weight.

• Definition

  ChEBI: D-keto-manno-heptulose is the open chain form of D-manno-heptulose.

D-manno-2-Heptulose Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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