Chlormephos (ISO)

Bezeichnung:Chlormephos (ISO)

CAS-Nr24934-91-6

Englisch Name:CHLORMEPHOS

CBNumberCB4364182

SummenformelC5H12ClO2PS2

Molgewicht234.7

MOL-Datei24934-91-6.mol

Synonyma

Chlormephos

Chlormephos (ISO)

Chlormethylphos

Chlormephos (ISO) physikalisch-chemischer Eigenschaften

Schmelzpunkt	25°C
Siedepunkt	bp1mm 93-95°; bp0.1 Torr 81-85°
Dichte	d20 1.260
Dampfdruck	7.6 Pa (30 °C)
Brechungsindex	nD220 1.5244
Flammpunkt	100 °C
storage temp.	0-6°C
Wasserlöslichkeit	60 mg l^-1(20 °C)
Aggregatzustand	liquid
EPA chemische Informationen	Chlormephos (24934-91-6)

Sicherheit

Kennzeichnung gefährlicher	T+,N
R-Sätze:	27/28-50/53
S-Sätze:	28-36/37-45-60-61-27
RIDADR	3018
RTECS-Nr.	TD5170000
HazardClass	6.1(a)
PackingGroup	II
Giftige Stoffe Daten	24934-91-6(Hazardous Substances Data)
Toxizität	LD50 in rats (mg/kg): 7 orally; 27 dermally; LC50 in fish: 1.5 mg/l (Lynch)

Gefahreninformationscode (GHS)

CHLORMEPHOS Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT
CHEMISCHE GEFAHREN
Die Substanz zersetzt sich beim Verbrennen unter Bildung von giftigen und ätzenden Rauchen mit Phosphoroxiden und Schwefeloxiden. Greift einige Metalle an.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt. BEI vorhanden.
MAK nicht festgelegt.
AUFNAHMEWEGE
Aufnahme in den Körper in gefährlichen Mengen durch Inhalation, über die Haut und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Cholinesterasehemmer. Möglich sind Auswirkungen auf das Nervensystem mit Krämpfen und Atemdepression. Exposition kann zum Tod führen. Die Auswirkungen treten u.U. verzögert ein. ärztliche Beobachtung notwendig.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Cholinesterasehemmer. Kumulative Wirkung möglich (s. AKUTE GEFAHREN/SYMPTOME).
LECKAGE
Persönliche Schutzausrüstung: Vollschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät. NICHT in die Umwelt gelangen lassen. Ausgelaufene Flüssigkeit in abdichtbaren Kunststoff-Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen.
R-Sätze Betriebsanweisung:
R27/28:Sehr giftig bei Berührung mit der Haut und beim Verschlucken.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Chlormephos is an organophosphate, colorlessliquid. Molecular weight=234.70; Boiling point =81-85℃ at 0.1 mmHg. Hazard Identification (based onNFPA 704 M Rating System): Health 3, Flammability 2,Reactivity 0. Soluble in water; solubility=60 mg/L at20℃.
Verwenden
Insecticide primarily for soil applications.
Verwenden
Chlormefos has agricultural applications. Useful for preparing compositions for controlling plant diseases.
Verwenden
Chlormephos is used to control soil insects such as wireworms in a number of crops.
Definition
ChEBI: Chlormephos is an organic thiophosphate, an organothiophosphate insecticide and an organochlorine insecticide. It has a role as an agrochemical and an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Allgemeine Beschreibung
Colorless liquid. Used as a soil insecticide. Not registered as a pesticide in the U.S.
Air & Water Reaktionen
Slightly soluble in water [Farm Chemicals Handbook].
Reaktivität anzeigen
Organophosphates, such as CHLORMEPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health Hazard
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) CHLORMEPHOS is poisonous; it may be fatal if inhaled, swallowed, or absorbed through the skin.
Brandgefahr
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire and runoff from control water may produce irritating or poisonous gases.
mögliche Exposition
This material is a soil insecticide. Notregistered as a pesticide in the US.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If this chemicalhas been inhaled, remove from exposure, begin rescuebreathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart actionhas stopped. Transfer promptly to a medical facility. Whenthis chemical has been swallowed, get medical attention.Give large quantities of water and induce vomiting. Do notmake an unconscious person vomit. Medical observation isrecommended for 24-48 h after breathing overexposure, aspulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consideradministering a corticosteroid spray.
Stoffwechselwegen
Chlormephos is a soil insecticide with considerable vapour phase activity. The main soil metabolite is ethion. The mechanism of hydrolysis of chlormephos is mainly by the nucleophilic attack of OH- on the Smethylene carbon to yield O,O-diethyl phosphorodithioate and in this respect it is similar to mecarbam. This mechanism may afford ethion when the nucleophile is O,O-diethyl phosphorodithioate. The other mechanism of hydrolysis is by attack on phosphorus to yield O,O-diethyl phosphorothioate and these two routes of hydrolytic degradation apparently dominate the metabolism of the insecticide.
Stoffwechsel
In soils, chlormephos is converted to ethion by reaction with the hydrolytic product, O,O-diethyl hydrogen phosphorothioate.
Lager
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working withChlormephos you should be trained on its proper handlingand storage. Should be protected from moisture and storedin glass-lined or polyethylene-lined containers. Keep awayfrom strong oxidizers. Sources of ignition, such as smokingand open flames, are prohibited where this chemical isused, handled, or stored in a manner that could create apotential fire or explosion hazard.
Versand/Shipping
This chemical requires a shipping label of“POISONOUS/TOXIC MATERIALS” for organophosphorus pesticides, liquid, toxic. It falls in Hazard Class6.1.
Toxicity evaluation
The acute oral LD₅₀ for rats is 7 mg/kg. NOEL (90 d) for rats is 0.39 mg/kg diet (0.002 mg/kg/d). In rats, orally administered chlormephos is almost completely eliminated within 24 h in the urine as diethyl hydrogen phosphate and O,O-diethyl hydrogen phosphorothioate.
Degradation
In strongly basic solution (0.5 M aqueous KOH), hydroxide ion attack on chlormephos may occur on the phosphorus atom with P-C bond cleavage to yield O,O-diethyl phosphorothioate (2) or on the S-methylene carbon atom to give O,O-diethyl phosphorodithioate (3), both of which may react with chlormephos to give further products. Hudson et al. (1991) showed that both hydrolysis products 2 and 3 could react with chlormephos via attact on the ethoxy group to yield the transethylation products O,O,Striethyl phophorothioate (4) and O,O,S-triethyl phophoroditluoate (5) respectively. Compound 3 could also attack the phosphorus atom of chlormephos to yield O,O,O’,O’-tetraethyl trithiopyrophosphate (6) and the S-methylene carbon to give ethion (7). Reaction products were identified by GC-MS after conversion of the acidic products into their methyl esters by reaction with diazomethane. Routes by which these products may be formed in strongly basic solution are shown in Scheme 1.
Inkompatibilitäten
Contact with oxidizers may cause therelease of phosphorous oxides. Contact with strong reducingagents, such as hydrides, may cause the formation of flammable and toxic phosphine gas. Contact with alkaline materials causes rapid hydrolysis. May corrode metals.

24934-91-6, CHLORMEPHOS Verwandte Suche:

Send Inquriy