Wnt Agonist

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

• Sicherheit

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Wnt Agonist Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  CID 11210285 hydrochloride has been used as a Wnt agonist.

• Definition

  ChEBI: N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine is a member of pyrimidines.

• Biologische Aktivität

  wnt agonist 1 is a small-molecule agonist of wnt signaling pathway [1].the wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation [1].wnt agonist 1 is a cell-permeable wnt signaling pathway agonist. wnt agonist 1 induced b-catenin- and tcf-dependent transcriptional activity in a dose-dependent way with ec50 of 0.7 μm. in xenopus embryos, treatment with wnt agonist 1 (10 μm) from developmental stage 10.5 to stage 40 resulted in substantial head defects, such as diminished heads and complete loss of eyes, and reduced eyes and heads. this phenotype is similar to that which results from wnt over-expression in head specification during early embryonic development.

• Biochem/physiol Actions

  CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist.

• Einzelnachweise

  liu j, wu x, mitchell b, et al. a small-molecule agonist of the wnt signaling pathway. angew chem int ed engl. 2005 mar 18;44(13):1987-90.

Wnt Agonist Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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