BroModifluoroMethyl phenyl sulfone

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P302+P352：BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

BroModifluoroMethyl phenyl sulfone Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  The nucleophilic reactions of bromodifluoromethyl phenyl sulfone with electrophiles such as aldehydes in the presence of TDAE affords (phenylsulfonyl)difluoromethyl-containing synthetically useful intermediates. Palladium-mediated reactions of styrene derivatives, vinyl ethers, and heteroaromatics with bromodifluoromethyl phenyl sulfone in the presence of potassium carbonate affords the (phenylsulfonyl)difluoromethylated products.

• Verwenden

  Bromodifluoromethyl phenyl sulfone is an intermediate component in the synthesis of (phenylsulfonyl)difluoromethyl and can be used to prepare (phenylsulfonyl)difluoromethylated products by palladium-mediated reactions.

• Verwenden

  Bromodifluoromethyl Phenyl Sulfone can be used to prepare difluoromethyl ethers via difluoromethylation of alcohols.

• Reaktionen

  (1) Difluoromethylation of aldehydes.
  
  (2) Difluoromethylation of styrenes, vinyl ethers, and heteroaromatics.
  
  

• Einzelnachweise

  [1] G.K. SURYA PRAKASH . Nucleophilic difluoromethylation and difluoromethylenation using bromodifluoromethyl phenyl sulfone[J]. Journal of Fluorine Chemistry, 2005. DOI:10.1016/j.jfluchem.2005.07.011.
  [2] NAKIN SURAPANICH. ChemInform Abstract: Palladium-Mediated Heck-Type Reactions of [(Bromodifluoromethyl)sulfonyl]benzene: Synthesis of α-Alkenyl- and α-Heteroaryl-Substituted α,α-Difluoromethyl Phenyl Sulfones.[J]. ChemInform, 2013. DOI:10.1002/chin.201314090.
  

BroModifluoroMethyl phenyl sulfone Upstream-Materialien And Downstream Produkte

BroModifluoroMethyl phenyl sulfone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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