Dithiazaniniodid

Bezeichnung:Dithiazaniniodid

CAS-Nr514-73-8

Englisch Name:3,3'-DIETHYLTHIADICARBOCYANINE IODIDE

CBNumberCB4122269

SummenformelC23H23IN2S2

Molgewicht518.48

MOL-Datei514-73-8.mol

Synonyma

Dithiazaniniodid

Dithiazaniniodid physikalisch-chemischer Eigenschaften

Schmelzpunkt	249 °C (dec.) (lit.)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Soluble in methanol
Aggregatzustand	Powder
Farbe	Green
Merck	14,3369
BRN	3838938
EPA chemische Informationen	Dithiazanine iodide (514-73-8)

Sicherheit

Kennzeichnung gefährlicher	T+
R-Sätze:	28-36/37/38
S-Sätze:	26-28-36/37-45
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS-Nr.	DL7060000
F	8
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29309099
Giftige Stoffe Daten	514-73-8(Hazardous Substances Data)
Toxizität	LD50 intraperitoneal in mouse: 3mg/kg

Gefahreninformationscode (GHS)

3,3'-DIETHYLTHIADICARBOCYANINE IODIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R28:Sehr giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Dithiazanine iodide is a green, needle-likecrystalline solid which decomposes at 248℃. Sulfur-likeodor. Molecular weight= 519.51. Melting point 5 225℃;Hazard Identification (based on NFPA-704 M RatingSystem): Health 3, Flammability 0, Reactivity 1. Insolublein water.
Chemische Eigenschaften
green crystalline powder
Originator
Delvex,Lilly,US,1958
Verwenden
It is employed as a solvent soluble laser dye. DTDCi is used as fluorescent contrast agent in three-dimensional fluorescence lifetime tomography and as a dye for rapid genetic screening. It is a potential sensitive probe useful for fluorometric analysis of transferable membrane pores and effects of membrane potential on Na cotransports in eel intestinal brush-border membrane vesicles.
Verwenden
Sensitizer for photographic emulsions.
Verwenden
DTDCi is used as;
- Fluorescent contrast agent in three-dimensional fluorescence lifetime tomography.
- Dye for rapid genetic screening.
Manufacturing Process
3.05 g of 1-methylbenzthiazole ethiodide, 1.11 g of β-ethyl thio acrolein diethyl acetal and 15 cc of pyridine were mixed and boiled gently under reflux for 15 minutes. The reaction mixture was then poured into an aqueous solution of potassium iodide. The dye was precipitated and was filtered off, and washed with ethyl alcohol and ether. Recrystallization from methyl alcohol solution yielded the dye as green needles. Melting point 248°C with decomposition.
Trademarks
Abminthic;Anguifugan;D.i.m.;Deselmine;Dilombrine;Dithiazine (dye);Dizan;Eastman 7663;Elmizin;Nekel;Omni-passin;Ossiurene;Telmicid;Telmide.
Therapeutic Function
Anthelmintic
Weltgesundheitsorganisation (WHO)
Dithiazanine iodide, an anthelminthic, was introduced in 1959 for the treatment of strongyloid worms and whipworms. Between 1961 and 1964 its use was associated with eight fatal cases of severe acidosis and shock. Although the drug is not significantly absorbed from the gut, in normal circumstances it was assumed that these fatalities were due to atypically high uptake from inflamed intestinal mucosa. Dithiazanine iodide has been superseded by safer and more effective drugs; however, it may remain available in some countries.
Allgemeine Beschreibung
Green, needle-like crystals. Used as a veterinary anthelmintic, as a sensitizer for photographic emulsions and as an insecticides. Not registered as a pesticide in the U.S.
Reaktivität anzeigen
An amine, organosulfide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
Highly toxic by mouth. (Non-Specific -- Pesticide, Solid, n.o.s.) Poisonous if swallowed, or if dust is inhaled.
Brandgefahr
When heated to decomposition, 3,3'-DIETHYLTHIADICARBOCYANINE IODIDE emits toxic fumes of iodine, sulfur oxides, and nitrogen oxides.
Sicherheitsprofil
Poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits very toxic fumes of I-, SOx, and NOx. See also IODIDES.
mögliche Exposition
This material is used as a plasticizer,as a rubber accelerator; and as an intermediate inmanufacturing of pesticides
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Lager
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area.
Versand/Shipping
Pesticides, solid, toxic, n.o.s. have a labelrequirement of “POISONOUS/TOXIC MATERIALS.”They fall in Hazard Class 6.1 and this material in PackingGroup II.
Inkompatibilitäten
Stable under normal conditions of temperature and pressure. Keep away from alkalies, strongoxidizers.

3,3'-DIETHYLTHIADICARBOCYANINE IODIDE Upstream-Materialien And Downstream Produkte

Dithiazaniniodid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

514-73-8, 3,3'-DIETHYLTHIADICARBOCYANINE IODIDE Verwandte Suche:

Send Inquriy