Metiazininsure

metiazinic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Soripan,Specia,France,1970

• Definition

  ChEBI: Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.

• Manufacturing Process

  10-Methyl-3-acetylphenthiazine is prepared in accordance with G. Cauquil and A. Casadevall, Bull. Soc.Chim., p 768 (1955). (10-Methyl-3-phenthiazinyl)acetic acid (MP 146°C; 21.4 g) is prepared by Willgerodt's reaction (action of sulfur and morpholine, followed by hydrolysis) employing 10-methyl-3-acetylphenthiazine as starting material.

• Therapeutic Function

  Antiinflammatory

• Handelsname

  Roimal (Kantoishi, Japan), Soripal (Torii, Japan).

• Synthese

  Metiazinic acid is prepared via the Willgerodt reaction (sulfur and morpholine) from 2-acetyl-10-methylphenothiazine.
  

• Dosage

  Metiazinic acid has been beneficial to arthritis patients when given at a daily dose of 0.75 – 1.5 g/d.

metiazinic acid Upstream-Materialien And Downstream Produkte

Metiazininsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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