Sulfacarbamide Struktur

Sulfacarbamid

Bezeichnung:Sulfacarbamid

CAS-Nr547-44-4

Englisch Name:Sulfacarbamide

CBNumberCB3711796

SummenformelC7H9N3O3S

Molgewicht215.23

MOL-Datei547-44-4.mol

Synonyma

Sulfacarbamid

Sulfacarbamid physikalisch-chemischer Eigenschaften

Schmelzpunkt	146-148° (slight dec)
Dichte	1.4565 (rough estimate)
Brechungsindex	1.6630 (estimate)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
Löslichkeit	DMSO : ≥ 28 mg/mL (130.09 mM)
Aggregatzustand	Solid
pka	pKa 1.78(H2O t = 25 I = 0.05) (Uncertain);5.42(H2O t = 25 I = 0.05) (Uncertain)
Farbe	White to off-white
Wasserlöslichkeit	2.333g/L(20 ºC)
InChI	InChI=1S/C7H9N3O3S/c8-5-1-3-6(4-2-5)14(12,13)10-7(9)11/h1-4H,8H2,(H3,9,10,11)
InChIKey	WVAKABMNNSMCDK-UHFFFAOYSA-N
SMILES	C1(S(NC(N)=O)(=O)=O)=CC=C(N)C=C1

Gefahreninformationscode (GHS)

Sulfacarbamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Sulfacarbamide is a blood sugar-lowering drug, also acting on the vegetative nervous system.
Chemische Eigenschaften
White solid
Verwenden
antibacterial
Verwenden
Sulfacarbamide-d4 is the labeled analogue of Sulfacarbamide (S688945), an antibiotic which is rapidly absorbed in blister fluid.
Definition
ChEBI: Sulfacarbamide is a sulfonamide and a member of benzenes.
Weltgesundheitsorganisation (WHO)
Sulfacarbamide, a sulfonamide anti-infective agent, was introduced in the 1940's for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. The Sulfacarbamide are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfacarbamide still remains available in at least one country for the treatment of urinary infections.
Mechanism of action
Sulfonylureas bind to and inhibit the ATP-sensitive potassium channels (K) on the pancreatic beta cells. As a result, potassium efflux decreases, and the beta-cell membrane depolarizes. Membrane depolarization causes calcium channels to open, leading to calcium influx and increased intracellular calcium, which stimulates insulin secretion from the pancreatic beta cells. Sulfonylureas cause insulin release regardless of blood glucose levels.

Sulfacarbamide Upstream-Materialien And Downstream Produkte

Sulfacarbamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

547-44-4, Sulfacarbamide Verwandte Suche:

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