FIBROBLAST GROWTH FACTOR, BASIC, HUMAN

FIBROBLAST GROWTH FACTOR, BASIC, HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden

• Allgemeine Beschreibung

  FGF-2 (fibroblast growth factor 2) is a basic heparin binding growth factor. It is ubiquitously expressed and belongs to the FGF family. It is also referred to as BFGF (basic fibroblast growth factor). The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

• Biochem/physiol Actions

  FGF-2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. It is present in the preimplantation embryos and is important for proper development. It is also responsible for angiogenesis. FGF-2 plays a crucial role in adipogenesis and development of adipose tissues. It is associated with tumor growth and metastasis.

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