Fmoc-Orn(Boc)-OH

Bezeichnung:Fmoc-Orn(Boc)-OH

CAS-Nr109425-55-0

Englisch Name:Fmoc-Orn(Boc)-OH

CBNumberCB2489395

SummenformelC25H30N2O6

Molgewicht454.52

MOL-Datei109425-55-0.mol

Fmoc-Orn(Boc)-OH physikalisch-chemischer Eigenschaften

Schmelzpunkt	111-115℃
Siedepunkt	679.0±55.0 °C(Predicted)
Dichte	1.226±0.06 g/cm3(Predicted)
storage temp.	2-8°C
Löslichkeit	soluble in Methanol
Aggregatzustand	powder to crystal
pka	3.85±0.21(Predicted)
Farbe	White to Almost white
BRN	4772025
InChIKey	JOOIZTMAHNLNHE-NRFANRHFSA-N
SMILES	C(O)(=O)[C@H](CCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS Datenbank	109425-55-0(CAS DataBase Reference)

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29242990

Gefahreninformationscode (GHS)

Fmoc-Orn(Boc)-OH Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Fmoc-Orn(Boc)-OH is an ornithine-containing amino acid building block. It has been used to conjugate ornithine to GFP-labeled peptides, enhancing cell permeability when compared to unconjugated GFP-labeled peptides. This compound is useful in preparing cyclic peptides and special arginine derivates.
Chemische Eigenschaften
White powder
Verwenden
Fmoc-Orn(Boc)-OH is a biochemical reagent. It can be used as a biomaterial or organic compound in life science-related research.
synthetische
2 mmol L-Orn was weighted and dissolved in 15 ml of acetonitrile; 16 mmol Boc2O was dissolved in acetonitrile and added dropwise to an acetonitrile solution of ornithine, to react and generate a complex; 10 ml 20% sodium bicarbonate aqueous solution was added, and 2 g of anhydrous sodium carbonate and an appropriate amount of 8-hydroxyquinoline were added in batches; the mixture was stirred and reacted at room temperature for 4 hours to remove copper ions in the complex; then 2 mmol Fmoc-OSu was added to the aforesaid solution, followed by stirring at room temperature for 2 hours; the resultant was recrystallized with an ethyl acetate/petroleum ether mixed solvent, to obtain a peptide head intermediate Fmoc-Orn(Boc)-OH.
reaction suitability
Reaction type: Fmoc solid-phase peptide synthesis
Solubility in organics
DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml

Fmoc-Orn(Boc)-OH Upstream-Materialien And Downstream Produkte

Fmoc-Orn(Boc)-OH Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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