Talampicillin

TALAMPICILLIN Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Talpen,Beecham,US,1975

• Verwenden

  Antibacterial.

• Definition

  ChEBI: Talampicillin is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin. It is a prodrug of ampicillin. It has a role as a prodrug. It is functionally related to an ampicillin and an o-phthalaldehydic acid.

• Manufacturing Process

  A fine suspension of 25.18 grams (0.05 mol) of potassium salt of enamine protected ampicillin and 10.65 grams (0.05 mol) 3-bromophthalide were reacted in a 1:2 mixture of acetone/ethyl acetate (1,500 ml) for 24 hours. After filtration the organic layer was washed twice with 250 ml portions of 1 N sodium bicarbonate and brine, dried over anhydrous magnesium sulfate and concentrated in vacuo. Addition of ether crystallized the phthalide enamine protected α-aminophenylacetamido penicillanate in 85% yield.

• Therapeutic Function

  Antibacterial

Talampicillin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(17)Suppliers

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