Amphotalid

amphotalide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Amphotalide,ZYF Pharm Chemical

• Definition

  ChEBI: Amphotalide is a member of phthalimides.

• Manufacturing Process

  A mixture of 5-phthalimidopentyl bromide (Drake and Garman, J.Amer. Chem. Sec, 1949, 71, 2426) (296.0 g) and potassium p-nitrophenoxide (177.0 g) in ethanol (1.5 L) was stirred mechanically, boiled under reflux for 20 h, concentrated to half its volume, cooled and filtered. The product was washed with water, dried and crystallised from acetone, giving 1-p-nitrophenoxy-5- phthalimidopentane, melting point 123°-124°C.
  The foregoing 1-p-nitrophenoxy-5-phthalimidopentane (100.0 g) in ethanol (1 L) was reduced by hydrogen over 2% of platinum oxide at 74°C/73 lb. per sq. in. The filtered solution on cooling gave L-p-aminophenoxy-5-phthalimidopentane, melting point 111°-112° C (recrystallisation from ethanol).

• Therapeutic Function

  Antischistosomal

amphotalide Upstream-Materialien And Downstream Produkte

Amphotalid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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