6-Keto prostaglandin f1alpha-d4

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6-Keto prostaglandin f1alpha-d4 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  6-keto Prostaglandin F_1α-d₄ (6-keto PGF_1α-d₄) contains four deuterium atoms at the 3, 3'', 4, and 4'' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF_1α by GC- or LC-MS. 6-keto PGF_1α is the inactive, non-enzymatic hydrolysis product of PGI₂. 6-keto PGF_1α serves as a useful marker of PGI₂ biosynthesis in vivo. When [³H]-PGI₂ is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [³H]-6-keto PGF_1α.

• Verwenden

  6-keto Prostaglandin F1α-d4 is the deuterium labeled 6-keto Prostaglandin F1α[1].

• Einzelnachweise

  [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110

6-Keto prostaglandin f1alpha-d4 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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