AG 825

AG 825 Chemische Eigenschaften,Einsatz,Produktion Methoden

• S-Sätze Betriebsanweisung:

  S22:Staub nicht einatmen.
  S24/25:Berührung mit den Augen und der Haut vermeiden.

• Verwenden

  A selective ErbB2 inhibitor

• Verwenden

  AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer.

• Definition

  ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

• Biologische Aktivität

  Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

• Lager

  Store at +4°C

AG 825 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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