Dihydroresveratrol

Bezeichnung:Dihydroresveratrol

CAS-Nr58436-28-5

Englisch Name:Dihydroresveratrol

CBNumberCB11470201

SummenformelC14H14O3

Molgewicht230.26

MOL-Datei58436-28-5.mol

Dihydroresveratrol physikalisch-chemischer Eigenschaften

Schmelzpunkt	155-157°C
Siedepunkt	430.3±14.0 °C(Predicted)
Dichte	1.291±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 30 mg/ml).
pka	9.51±0.10(Predicted)
Aggregatzustand	solid
Farbe	Off-white
Stabilität	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Dihydroresveratrol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Dihydroresveratrol (58436-28-5) is a metabolite of resveratrol produced by gut microbiota.1-3?Glucoronide conjugates are found in human urine after oral intake of resveratrol-containing dietary supplements.4?Dihydroresveratrol glucoside is a potent melanogenesis inhibitor in B16F0 melanoma cells.5?Inactive analog of resveratrol in induction of premature senescence.6
Verwenden
Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are detectable in urine. The physiological effects of dihydroresveratrol have not been investigated.
Verwenden
Dihydroresveratrol is a natural phytoestrogen.
Definition
ChEBI: Dihydroresveratrol is a stilbenol that is 1,1'-ethane-1,2-diyldibenzene with hydroxy groups at positions 1, 3 and 4'. It has a role as a xenobiotic metabolite and a plant metabolite.
Einzelnachweise
1) Jung?et al.?(2009),?Interaction of dietary resveratrol with animal-associated bacteria; FEMS Microbiol. Lett.,?297?266 2) Bode?et al.?(2013),?In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota; Am. J. Clin. Nutr.,?97?295 3) Jarosova?et al.?(2019),?Metabolism of Stilbenoids by Human Faecal Microbiota; Molecules,?24?E1155 4) Radco?et al.?(2013),?Semi-preparative isolation of dihydroresveratrol-3-O-?-d-glucuronide and four resveratrol conjugates from human urine after oral intake of a resveratrol-containing dietary supplement; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 930?54 5) Oode?et al.?(2014),?Synthesis of dihydroresveratrol glycosides and evaluation of their activity against melanogenesis in B16F0 melanoma cells; Eur. J. Med. Chem.,?87?862 6) Faragher?et al.?(2011),?Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts; Age (Dordr.),?33?555

Dihydroresveratrol Upstream-Materialien And Downstream Produkte

Dihydroresveratrol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

58436-28-5, Dihydroresveratrol Verwandte Suche:

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