Valganciclovir

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Valganciclovir Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Antiviral.

• Verwenden

  Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.

• Definition

  ChEBI: The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.

• Indications

  Valganciclovir (Valcyte) is the L-valyl ester prodrug of ganciclovir.

• Trademarks

  Valcyte (Roche).

• Clinical Use

  Oral valganciclovir is comparable to intravenous ganciclovir for the treatment and suppression of CMV retinitis in AIDS patients.

• Arzneimittelwechselwirkung

  Potentially hazardous interactions with other drugs
  Antibacterials: increased risk of convulsions with imipenem-cilastatin.
  Antivirals: possibly increased didanosine concentration; profound myelosuppression with zidovudine - avoid if possible.
  Mycophenolate: possibly increased concentrations of both mycophenolic acid and ganciclovir.
  Increased risk of myelosuppression with other myelosuppressive drugs.

• Stoffwechsel

  Valganciclovir is well absorbed from the gastrointestinal tract and rapidly and extensively metabolised in the intestinal wall and liver to ganciclovir. Valganciclovir is eliminated in the urine as unchanged ganciclovir, mainly by glomerular filtration and also active tubular secretion.

Valganciclovir Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(120)Suppliers

175865-60-8, Valganciclovir Verwandte Suche: