TH

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H317：Kann allergische Hautreaktionen verursachen.

  H412：Schädlich für Wasserorganismen, mit langfristiger Wirkung.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P272：Kontaminierte Arbeitskleidung nicht außerhalb des Arbeitsplatzes tragen.

  P273：Freisetzung in die Umwelt vermeiden.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P302+P352：BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

  P333+P313：Bei Hautreizung oder -ausschlag: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

TH Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  An enzyme that is located in catecholamine-synthesizing cells and is responsible for the hydroxylation of L-tyrosine to L 3,4-dihydroxyphenylalanine (L-dopa). This is the initial and rate-limiting step in the biosynthetic pathway for catecholamines (dopamine, norepinephrine, and epinephrine). In addition to hydroxylating tyrosine using biopterin as a coenzyme, this enzyme can also hydroxylate phenylalanine to tyrosine. The enzyme is located in the cytosol of catecholamine neurons and has a Km for tyrosine that is in the micromolar range.

• Verwenden

  Anti-th antibody produced in rabbit has been used in:
  
  • western blotting (1:1000)
  • whole retinal flat-mount immunolabelling (1:500)
  • immunofluorescence (2:1000)
  • immunohistochemistry (2:1000)
  
  

• Allgemeine Beschreibung

  Tyrosine hydroxylase?(TH) is a cytoplasmic enzyme. The TH gene codes for a monooxygenase.

• Biochem/physiol Actions

  Cell surface-associated protein is implicated in virulence. Promotes bacterial attachment exclusively to the γ-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis. Enhances spleen cell proliferative response in vitro, contributing significantly to the immunostimulatory activity of S.aureus.

TH Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(34)Suppliers