3-(2-Methylaminoethyl)indole Struktur

3-(2-Methylaminoethyl)indol

Bezeichnung:3-(2-Methylaminoethyl)indol

Englisch Name:3-(2-Methylaminoethyl)indole

CBNumberCB0200967

SummenformelC11H14N2

Molgewicht174.24

Synonyma

3-(2-Methylaminoethyl)indol

3-(2-Methylaminoethyl)indol physikalisch-chemischer Eigenschaften

Schmelzpunkt	87-89 °C(lit.)
Siedepunkt	295.23°C (rough estimate)
Dichte	0.9649 (rough estimate)
Brechungsindex	1.6210 (estimate)
storage temp.	-20°C
Löslichkeit	DMF: 11 mg/ml; DMSO: 5 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml; Methanol: 1 mg/ml
Aggregatzustand	Shiny Crystalline Powder or Flakes
pka	17.26±0.30(Predicted)
Farbe	White to off-white
InChI	InChI=1S/C11H14N2/c1-12-7-6-9-8-13-11-5-3-2-4-10(9)11/h2-5,8,12-13H,6-7H2,1H3
InChIKey	NCIKQJBVUNUXLW-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC=C2)C(CCNC)=C1
CAS Datenbank	61-49-4(CAS DataBase Reference)
NIST chemische Informationen	1H-Indole-3-ethanamine, N-methyl-(61-49-4)

Sicherheit

3-(2-Methylaminoethyl)indole Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to off-white shiny cryst. powder or flakes
Verwenden
Reactant for preparation of:• ;Manzamine analogues for the control of neuroinflammation and cerebral infections1• ;Serotonin 4 receptors (5-HT4) receptor agonists2• ;A sulful-containing indole alkaloid, glypetelotine3• ;Selective inhibitors of cyclin dependent kinase (CDK4)4• ;Antagonist of the human tachykinin NK-2 receptor5• ;Inhibitors of the tyrosine-specific protein kinase pp60c-src SH2 Domain6
Verwenden
N-Methyltryptamine is an alkylamine, a putative hallucinogen constituent from the root of Mimosa ophthalmocentra. An alkaloid from the leaves of Hammada scoparia.
Verwenden
N-Methyltryptamine (NMT) is a naturally-occurring tryptamine which may be derived from L-tryptophan or, indirectly, from serotonin. While substituted NMTs are psychoactive through their effects on monoamine action, NMT appears to be rapidly metabolized by monoamine oxidases. This product is intended for research and forensic applications.[Cayman Chemical]
Definition
ChEBI: N-methyltryptamine is a tryptamine alkaloid and a member of tryptamines. It has a role as a metabolite. It is functionally related to a tryptamine. It is a conjugate base of a N-methyltryptaminium.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 49, p. 87, 2001
Journal of Medicinal Chemistry, 19, p. 99, 1976 DOI: 10.1021/jm00223a016