inulicin

inulicin Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  Inulicin (1-O-Acetylbritannilactone) is an active compound isolated from Inula Britannica L. It inhibits VEGF-mediated activation of Src and FAK. It also inhibits LPS-induced PGE2 production and COX-2 expression, as well as NF-κB activation and translocation.

• in vivo

  Administration of a single dose of Inulicin (1-O-Acetylbritannilactone; 12 mg/kg/day) remarkably suppresses growth of A549 xenografts in nude mice. In vivo microvessels formation and Src activation are also significantly inhibited in Inulicin-treated xenograft tumors. To investigate the potential activity of Inulicin in vivo, a nude mice xenograft model is applied.

• target

  NF-κB < span>

  COX-2

inulicin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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