Anisacril

Anisacril Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  SCF 16046,Smith Kline

• Manufacturing Process

  A solution of Grignard reactive (prepared from 247 g of o-bromoanisole and 31.6 g of magnesium in 1500 ml of ether) is added dropwise to a solution of 91 g of diphenyl pyruvic acid in ether. The mixture is refluxed for 2 hours. After cooling to the reaction mixture is added 5% hydrochloric acid and the product is extracted with 5% solution of sodium hydroxide. α-(o-Anisyl)-β,β- diphenyl lactic acid is precipitated by addition of concentrated hydrochloric acid; yield 62 g, melting point 194-195°C.
  4 g of α-(o-anisyl)-β,β-diphenyl lactic acid is heated at 210-215°C for 10-15 min. The α-(o-anisyl)-β,β-diphenyl acrylic acid is recrystallized from benzene, yield 2.85 g (74%), melting point 195-196°C.

• Therapeutic Function

  Anorexic, Antihyperlipidemic

Anisacril Upstream-Materialien And Downstream Produkte

Anisacril Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(1)Suppliers

5129-14-6, Anisacril Verwandte Suche: