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ChemicalBook  CAS数据库列表  兔抗猪IGG H&L (HRP)

兔抗猪IGG H&L (HRP)

产品描述 宿主 免疫原 偶联物 靶标种属 经验证的应用 背景 下游应用
兔抗猪IGG H&L (HRP),,结构式
兔抗猪IGG H&L (HRP)
  • CAS号:
  • 英文名:Rabbit Anti-Pig IgG H&L (HRP)
  • 中文名:兔抗猪IGG H&L (HRP)
  • CBNumber:CB96305469
  • 分子式:
  • 分子量:0
  • MOL File:Mol file

兔抗猪IGG H&L (HRP)性质、用途与生产工艺

  • 产品描述

    兔多克隆抗体二抗to猪IgG - H&L (HRP)

  • 宿主 Rabbit
  • 免疫原 Highly purified whole immunoglobulin from Pig.
  • 偶联物 HRP
  • 靶标种属 Pig
  • 经验证的应用 IHC-Fr, IHC-P, Flow Cyt, ELISA, WB, ICC
  • 背景 As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (5 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. Protein G or Protein A on the surface of certain Staphylococcal and Streptococcal strains specifically binds with the Fc region of IgGs, and has numerous applications in biotechnology as a reagent for affinity purification. Recombinant IgG Fc Region is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.

  • 下游应用 兔抗猪IGG H&L(HRP)是以猪IGG H&L为抗原的HRP山羊多克隆抗体，可以特异性结合猪IGG H&L。兔抗猪IGG H&L(HRP)主要用于ICC/IF,Dotblot,ELISA,IHC-P,IHC-Fr,Immunomicroscopy,WB等猪IGG H&L检测实验。
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