ChemicalBook CAS数据库列表 (2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
生物活性 体外研究
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 试剂级价格
- CAS号:1911578-83-0
- 英文名:(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
- 中文名:(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
- CBNumber:CB96225875
- 分子式:C24H29N6O8P
- 分子量:560.5
- MOL File:Mol file
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol化学性质
- 密度 :1.55±0.1 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 溶解度 :DMSO: 200 mg/mL (356.82 mM)
- 形态 :A crystalline solid
- 酸度系数(pKa) :12.00±0.70(Predicted)
- 颜色 :White to off-white
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol性质、用途与生产工艺
- 生物活性 Anti-virus agent 1 (compound 4i) 是 GS-5734 (HY-104077; Remdesivir) 的氨基磷酸酯前药,具有有效的抗病毒 (antiviral) 活性。Anti-virus agent 1 用于冠状病毒和埃博拉病毒 (EBOV) 的研究。
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体外研究
Anti-virus agent 1 (compound 4i) has antiviral activity for EBOV in HeLa cell (EC 50 =1845 nM), HMVEC cell (TERT-immortalized human foreskin microvascular endothelial cells; ATCC-4025; EC 50 =367 nM), human macrophages (EC 50 =297 nM). Anti-virus agent 1 has a CC 50 of 21 μM in MT4 cell (human leukemia T-cell).
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol上下游产品信息
上游原料
下游产品
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 试剂级价格
- 更新日期:2024/11/08
- 产品编号:HY-131233
- 产品名称:Anti-virus agent 1
- CAS编号:
- 包装:1 mg
- 价格:2136元
- 更新日期:2024/11/08
- 产品编号:HY-131233
- 产品名称:(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol Anti-virus agent 1
- CAS编号:1911578-83-0
- 包装:5mg
- 价格:4700元
(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol生产厂家
- 公司名称:SynZeal Research Pvt Ltd
- 联系电话:--
- 电子邮件:standards@synzeal.com
- 国家:印度
- 产品数:6514
- 优势度:58
1911578-83-0, (2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol相关搜索:
- Remdesivir impurity-1 2-ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate 瑞德西韦全套杂质 R-18 Remdesivir Impurity 44 瑞德西韦杂质5 (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol R-19-impurity 4 N-[(S)-(4-硝基苯氧基)苯氧基磷酰基]-L-丙氨酸异丙酯 瑞德西韦杂质 Remdesivir Impurity 39 (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate