ANTI-GAPDH 抗体

ANTI-GAPDH 抗体性质、用途与生产工艺

描述 GAPDH Antibody-Polyclonal Rabbit
宿主 Rabbit
种属反应性预测使用：Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
偶联性 Unconjugated
制备 This antibody was obtained from a rabbit immunized with A synthetic peptide corresponding to the center region of the human GAPDH.
验证的应用 WB
品牌示例
AVIVA SYSTEMS BIOLOGY
GAPDH Antibody - middle region (ARP40176_P050)
背景 ACTB (Actin Beta) is a Protein Coding gene. Diseases associated with ACTB include Dystonia, Juvenile-Onset and Baraitser-Winter Syndrome 1. Among its related pathways are Salivary secretion and Development Slit-Robo signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is ACTG1. TUBB, HPRT and ACTB were the most stably expressed genes for all analysis groups across meningioma and non-pathological meningeal tissue combined. ACTB, a significant upregulated gene in abdominal aortic aneurysm samples, could be regulated by CLIC4, which was significantly enriched in cell motions. Dystonia-deafness syndrome is a well-known clinical entity, with sensorineural deafness typically manifesting earlier than dystonia. ACTB p.Arg183Trp heterozygosity has been reported in six patients to cause combined infant-onset deafness and dystonia manifesting in adolescence or young adulthood.

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