生物活性 靶点 2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID 试剂级价格
ChemicalBook  CAS数据库列表  2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID

2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID

2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID,1061605-21-7,结构式
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID
  • CAS号:1061605-21-7
  • 英文名:Cereblon Ligand 1
  • 中文名:2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID
  • CBNumber:CB94666380
  • 分子式:C15H12N2O7
  • 分子量:332.27
  • MOL File:1061605-21-7.mol
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID化学性质
  • 沸点 :660.5±55.0 °C(Predicted)
  • 密度 :1.606±0.06 g/cm3(Predicted)
  • 溶解度 :Soluble in DCM
  • 形态 :A crystalline solid
  • 酸度系数(pKa) :2.95±0.10(Predicted)
  • 颜色 :White to off-white
  • InChI :InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21)
  • InChIKey :ZVWIXIGBWIEDFO-UHFFFAOYSA-N
  • SMILES :C(O)(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
安全信息
  • 海关编码 :2933998090

2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID性质、用途与生产工艺

  • 生物活性 Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3)是基于Thalidomide的 Cereblon (CRBN) 配体,可用于募集CRBN蛋白。Thalidomide-O-COOH (Cereblon ligand 3) 可以通过连接器与蛋白质的配体连接以形成 PROTACs (Proteolysis Targeting Chimera)。
  • 靶点
    TargetValue
    CRBN
    ()
  • 用途  一种用于PROTAC技术中的E3泛素连接酶的配体。
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID上下游产品信息
上游原料
下游产品
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID 试剂级价格
  • 更新日期:2024/11/11
  • 产品编号:XW02106160521705
  • 产品名称:2-((2-(2,6-二氧代哌啶-3-基)-1,3-二氧代异吲哚啉-4-基]氧基]乙酸 Thalidomide-O-COOH
  • CAS编号:
  • 包装:10g
  • 价格:5822元
  • 更新日期:2024/11/08
  • 产品编号:XW02106160521704
  • 产品名称:2-((2-(2,6-二氧代哌啶-3-基)-1,3-二氧代异吲哚啉-4-基]氧基]乙酸 Thalidomide-O-COOH
  • CAS编号:
  • 包装:5g
  • 价格:2911元
2-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL]OXY]ACETIC ACID生产厂家
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