7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸

7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸化学性质

熔点 :222-224 °C (dec.)(lit.)
沸点 :464.7±45.0 °C(Predicted)
密度 :1.317±0.06 g/cm3(Predicted)
储存条件 :Keep in dark place,Inert atmosphere,Room temperature
溶解度 :DMF: soluble
酸度系数(pKa) :-98.36 ± 0.20, most acidic, temperature: 25 °C; 6.06 ± 0.20, most basic(at 25℃)
形态 :Solid
颜色 :Bright orange solid; Orange crystals; Orange crystalline solid; Orange laths; Orange powder; Orange solid
最大波长(λmax) :409 nm (Buffer pH 9.0)
BRN :6145963
主要应用 :Epoxy resinsphotoluminescent devices;lithographic platematerials; oil-repellent copolymers/coatings;polymer matrices; silica nanoparticles for imaging,security, and sensing applications
生物领域应用 :Detecting hydrogenperoxide; evaluating iron ions; cysteine cathepsinsinhibitors; β-glucosidase inhibitors; humanmonoamine oxidase inhibitors; N-Methyl-D-aspartatereceptors (NMDARs) inhibitors; phosphateassay; probing actomyosin mechanism;treatingcancer/antitumor activity，treating cognitive deficits orschizophrenia;as a substrate for measuring proteinkinase activity

安全信息

7-(二乙胺基）-2-氧代-2-苯并吡喃-3-羧酸性质、用途与生产工艺

生物活性 7ACC1(DEAC; Coumarin D 1421; D 1421)能选择性干扰肿瘤微环境乳酸通量，能抑制表达MCT1和MCT4肿瘤细胞的乳酸涌入，但对乳酸流出无影响。

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