ChemicalBook CAS数据库列表 地诺前列素氨丁三醇
地诺前列素氨丁三醇
- CAS号:38562-01-5
- 英文名:Dinoprost tromethamine
- 中文名:地诺前列素氨丁三醇
- CBNumber:CB9394313
- 分子式:C24H45NO8
- 分子量:475.62
- MOL File:38562-01-5.mol
地诺前列素氨丁三醇化学性质
- 熔点 :100-101°
- 储存条件 :-20°C
- 溶解度 :H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.
- 形态 :powder
- 颜色 :white
- Merck :13,7970
- BRN :4087514
- 稳定性 :Hygroscopic
- InChIKey :IYGXEHDCSOYNKY-RZHHZEQLSA-N
安全信息
地诺前列素氨丁三醇性质、用途与生产工艺
- 生物活性 Dinoprost Tromethamine (Dinolytic, PGF2-alpha tham, Zinoprost, Prostin F2 alpha, Dinoprost Trometamol) 是一种合成的prostaglandin F2 alpha类似物，prostaglandin F2 alpha可通过直接作用于黄体素，刺激子宫肌层活性、使宫颈舒张、抑制黄体类固醇生成、诱导黄体溶解。
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靶点
FP Receptor
Human Endogenous Metabolite
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体外研究
Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt; 1 μM; for 24 hours) induces ER stress, autophagy, and apoptosis in goat luteal cells.
Dinoprost tromethamine salt (1 μM; for 24 hours) significantly increases the expression of GRP78 and UPR sensors.
Apoptosis Analysis
Cell Line: Goat luteal cells Concentration: 1 μM Incubation Time: For 24 hours Result: Significantly increased the apoptotic rate (15.62±3.12%). Cell Autophagy Assay
Cell Line: Goat luteal cells Concentration: 1 μM Incubation Time: For 24 hours Result: There was extensive overlap between LC3 and LAMP1 in luteal cells and autophagolysosomes were formed in goat luteal cells. Western Blot Analysis
Cell Line: Goat luteal cells Concentration: 1 μM Incubation Time: For 24 hours Result: The expression of GRP78 and UPR sensors including cleaved ATF6, phosphorylated-EIF2S1, EIF2S1, ATF4, phosphorylated-IRE1, autophagy-related protein LC3-II, and pro-apoptosis factor cleaved Caspase3 increased significantly in the cells.
地诺前列素氨丁三醇上下游产品信息
上游原料
下游产品
地诺前列素氨丁三醇 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-12956A
- 产品名称：Dinoprost tromethamine salt
- CAS编号：
- 包装：1 mg
- 价格：220元
- 更新日期：2024/11/08
- 产品编号：HY-12956A
- 产品名称：地诺前列素氨丁三醇 Dinoprost tromethamine salt
- CAS编号：38562-01-5
- 包装：5mg
- 价格：550元
地诺前列素氨丁三醇生产厂家
- 公司名称：DISCOVERY Importacao e Exportacao Ltda
- 联系电话：--
- 电子邮件：discovery@discoverychem.com.br
- 国家：巴西
- 产品数：390
- 优势度：58
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