ChemicalBook CAS数据库列表 马汉九里香碱
马汉九里香碱
- CAS号:21104-28-9
- 英文名:Mahanimbine
- 中文名:马汉九里香碱
- CBNumber:CB92056338
- 分子式:C23H25NO
- 分子量:331.45
- MOL File:21104-28-9.mol
马汉九里香碱化学性质
- 熔点 :94-95 °C
- 沸点 :502.6±39.0 °C(Predicted)
- 密度 :1.109
- 溶解度 :DMSO: 10 mM
- 酸度系数(pKa) :17.31±0.40(Predicted)
- 稳定性 :Light Sensitive
安全信息
- 危险类别码 :53
- WGK Germany :3
马汉九里香碱性质、用途与生产工艺
- 生物活性 Mahanimbine 是咖喱叶中的一种具有口服活性的生物碱。Mahanimbine 抑制高脂饮食 (HFD) 诱导的小鼠代谢并发症的进展。
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体内研究
Mahanimbine (2-4 mg/kg; p.o.; daily for 12 weeks) prevents HFD-induced weight gain in mice (male and female).
Mahanimbine prevented HFD-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with the restricted progression of systemic inflammation and oxidative stress.
Mahanimbine treatment improves glucose clearance and upregulates the expression of insulin responsive genes in liver and adipose tissue.Animal Model: Swiss albino mice (7-8 weeks old, both sex) Dosage: HFD+LD (2 mg/kg of body weight of mahanimbine), HFD+HD (4 mg/kg of body weight of mahanimbine); Administration: Oral suspension; daily for 12 weeks Result: Male HFD+LD and HFD+HD groups showed 51.70±6 3.59% and 47.37±3.73% weight gain, respectively, as compared with 71.02±6 6.04% in HFD fed mice whereas female HFD+LD and HFD+HD groups showed 24.31±1.68% and 25.10±2.61% weight gain as compared with HFD group with 36.69±3.60% of weight gain.
马汉九里香碱上下游产品信息
上游原料
下游产品
马汉九里香碱 试剂级价格
- 更新日期：2024/11/08
- 产品编号：HY-124557
- 产品名称：马汉九里香碱 Mahanimbine
- CAS编号：21104-28-9
- 包装：1mg
- 价格：11750元
- 更新日期：2023/03/20
- 产品编号：HY-124557
- 产品名称：马汉九里香碱 Mahanimbine
- CAS编号：21104-28-9
- 包装：5mg
- 价格：8200元
马汉九里香碱生产厂家
- 公司名称：SPECS
- 联系电话：--
- 电子邮件：info@specs.net
- 国家：荷兰
- 产品数：6833
- 优势度：70
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