ChemicalBook CAS数据库列表 模拟肽CROSSTIDE
模拟肽CROSSTIDE
- CAS号:171783-05-4
- 英文名:CROSSTIDE
- 中文名:模拟肽CROSSTIDE
- CBNumber:CB8972976
- 分子式:C48H77N17O17
- 分子量:1164.23
- MOL File:171783-05-4.mol
模拟肽CROSSTIDE化学性质
- 储存条件 :−20°C
- 溶解度 :H2O: soluble
- 形态 :lyophilized powder
- 颜色 :White to off-white
安全信息
- 安全说明 :22-24/25
- WGK Germany :3
模拟肽CROSSTIDE性质、用途与生产工艺
- 生物活性 Crosstide 是一种糖原合成酶激酶α/β融合蛋白序列的模拟肽,是 Akt 的底物。
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靶点
Akt
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体外研究
16HBE14o− cells exposed to RV39 demonstrate a crosstide kinase activity in vitro. Serine phosphorylation of crosstide is confirmed by immunoblotting, and phosphorylation is blocked by PP2 but not by PP3. The wildtype GST-AKT2 shows significant phosphoryl transferase activity towards crosstide, reaching an initial velocity of 16 pmol phosphate/min/μg enzyme. The mutant GST-AKT2T/E,S/D displayed an initial velocity of 85 pmol phosphate/min/μg kinase for phosphorylation of Crosstide, corresponding to a 5-fold increase compared to the wildtype enzyme.
模拟肽CROSSTIDE上下游产品信息
上游原料
下游产品
模拟肽CROSSTIDE生产厂家
- 公司名称:SIGMA
- 联系电话:--
- 电子邮件:
- 国家:瑞士
- 产品数:6896
- 优势度:91
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