ChemicalBook CAS数据库列表 106362-32-7
106362-32-7
- CAS号:106362-32-7
- 英文名:ALA-SER-THR-THR-THR-ASN-TYR-THR ACETATE
- 中文名:106362-32-7
- CBNumber:CB8497846
- 分子式:C35H55N9O16
- 分子量:857.86
- MOL File:106362-32-7.mol
106362-32-7化学性质
- 沸点 :1499.5±65.0 °C(Predicted)
- 密度 :1.432±0.06 g/cm3(Predicted)
- 储存条件 :-20°C
- 溶解度 :Soluble in DMSO
- 酸度系数(pKa) :3.21±0.10(Predicted)
- 形态 :Solid
- 颜色 :White to off-white
106362-32-7性质、用途与生产工艺
- 生物活性 Peptide T是源自HIV-1 gp120的V2区的八肽。 Peptide T是 CD4 受体的配体，可阻止 HIV 与CD4受体结合。
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靶点
CD4, HIV
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体外研究
Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4. Peptide T at 10 -8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10 -9 M concentration significantly inhibits IFN-g production by PBMC.
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体内研究
Peptide T is administered subcutaneously at different doses and phases of the experimental autoimmune encephalomyelitis (EAE) disease, but Peptide T neither prevents nor ameliorates EAE.
106362-32-7上下游产品信息
上游原料
下游产品
106362-32-7生产厂家
- 公司名称：SIGMA
- 联系电话：--
- 电子邮件：
- 国家：瑞士
- 产品数：6896
- 优势度：91
106362-32-7, 106362-32-7相关搜索:
- TYR-GLY-GLY-PHE-MET-LYS-LYS-MET-ASP-GLU-LEU-TYR-PRO-LEU-GLU-VAL-GLU-GLU-GLU-ALA-ASN-GLY-GLY-GLU-VAL-LEU-GLY-LYS-ARG-TYR-GLY-GLY-PHE-MET CONNEXIN 43 模拟肽 PHE-ALA-GLU-PRO-LEU-PRO-SER-GLU-GLU-GLU-GLY-GLU-SER-TYR-SER-LYS-GLU-VAL-PRO-GLU-MET-GLU-LYS-ARG-TYR-GLY-GLY-PHE-MET-ARG-PHE PEPTIDE M H-GLU-ARG-MET-ARG-PRO-ARG-LYS-ARG-GLN-GLY-SER-VAL-ARG-ARG-ARG-VAL-OH VAL-CIT-PAB 多肽合成 多肽杂质合成 多肽委托研发 成骨生长肽 (骨生长激素肽)(多肽) 多肽磷酸化标记 多肽荧光修饰 多肽委托生产 H-ASN-ALA-VAL-PRO-ASN-LEU-ARG-GLY-ASP-LEU-GLN-VAL-LEU-ALA-GLN-LYS-VAL-ALA-ARG-THR-OH 乙酰基-L-苏氨酸
