Amyloid beta-peptide (1-40) rat
- CAS号:144409-98-3
- 英文名:AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)
- 中文名:Amyloid beta-peptide (1-40) rat
- CBNumber:CB8293800
- 分子式:C190H291N51O57S
- 分子量:0
- MOL File:Mol file
- 储存条件 :-15°C
- 溶解度 :Soluble to 1 mg/ml in 1% Ammonia
- 形态 :Solid
- 颜色 :White to off-white
- 序列 :H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
Amyloid beta-peptide (1-40) rat性质、用途与生产工艺
- 生物活性 Amyloid β-peptide (1-40) (rat) 是蛋白水解切割淀粉样蛋白前体蛋白的易聚集产物，并且是在阿尔茨海默病脑中观察到的老年斑的主要成分。
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靶点
The Amyloid β-peptide (1-40) (rat)-treated rats require longer to find the platform hidden under the water. In the visible platform test, the latency for each group is similar (20.56±11.31 s in control and 14.68±9.97 s in Amyloid β-peptide (1-40) (rat) group, p=0.304). Among these tested proteins, 6 ones are significantly up-regulated and 7 ones significantly down-regulated in Amyloid β-peptide (1-40) (rat) group comparing with the control. Tubulin β chain is significantly down-regulated in Amyloid β-peptide (1-40) (rat) group (p=0.014) when compare with control. Similar changes are also observed for ATP synthase β subunit (p=0.010) and synapsin Ib between Amyloid β-peptide (1-40) (rat) and control groups, but not significantly for synapsin Ib (p=0.295).
- 多肽 Amyloid beta-peptide (1-40) rat是一种由淀粉样前体蛋白裂解后产生的一种容易聚集的多肽产物。在一些的动物实验中，Amyloid β-Protein (1-40) (mouse, rat)是阿尔茨海默病脑内老年斑块的主要组成部分。
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参考质量标准
外观:白色粉末
纯度(HPLC) ≥95.0%
醋酸根含量5.0%～12.0%
水分含量≤8.0%
肽含量≥70.0%
- 公司名称：Service Chemical Inc.
- 联系电话：--
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- 国家：德国
- 产品数：6350
- 优势度：71
- BETA- AMYLOID (1-16) Amyloid β-Protein (1-12) Amyloid β-Protein (5-42) Amyloid β-Protein (3-40) Amyloid Beta-Protein (1-14) BETA-淀粉样蛋白片断25-35 BETA-AMYLOID (1-28) Amyloid β-Protein (4-42) ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU MET-LEU-GLY-ILE-ILE-ALA-GLY-LYS-ASN-SER-GLY 淀粉Β-蛋白(1-43) BETA-AMYLOID(40-1) Amyloid β-Protein (1-6) H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-THR-VAL-ILE-VAL-OH Amyloid β-Protein (3-42)
