Β-酪啡肽-7

IC50: 14 μM (Opioid receptor)

β-Casomorphin, bovine (0.1 μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment.
β-Casomorphin, bovine (0.1 μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels.
β-Casomorphin, bovine do not modify the expression of rMuc1, rMuc4, and rMuc5AC.
β-Casomorphin, bovine (0.1 μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).

β-Casomorphin, bovine (7.5×10 ⁻⁶ mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats.
β-Casomorphin, bovine (7.5×10 ⁻⁶ mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats.
β-Casomorphin, bovine (7.5×10 ⁻⁶ mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats.
β-Casomorphin, bovine (7.5×10 ⁻⁶ mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.