ChemicalBook CAS数据库列表 TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2
- CAS号:88377-68-8
- 英文名:ADRENORPHIN
- 中文名:TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2
- CBNumber:CB8129589
- 分子式:C44H69N15O9S
- 分子量:984.18
- MOL File:88377-68-8.mol
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2化学性质
- 密度 :1.42±0.1 g/cm3(Predicted)
- 储存条件 :−20°C
- 溶解度 :insoluble in EtOH; ≥48.7 mg/mL in H2O; ≥98.4 mg/mL in DMSO
- 形态 :Solid
- 酸度系数(pKa) :9.97±0.15(Predicted)
- 颜色 :White to off-white
- 序列 :H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2
安全信息
- WGK Germany :3
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2性质、用途与生产工艺
- 生物活性 Adrenorphin 是一种阿片八肽，为 μ-opioid 受体激动剂，Ki 值为 12 nM。
-
靶点
Ki: 12 nM (μ-opioid receptor)
-
体外研究
Adrenorphin (Metorphamide) is a opioid octapeptide from bovine brain, acts as a potent agonist of μ-opioid receptor, with K i of 12 nM. The binding ratios of K i for μ-opioid receptor/K i for δ-opioid receptor of 0.04 and of K i for μ-opioid receptor/K i for κ-opioid receptor of 0.46. Adrenorphin potently inhibits catecholamine secretion evoked by 10 μM nicotine in cultured human pheochromocytoma 6 cells, with an IC 50 of 1.1 μM.
-
参考质量标准
外观:白色粉末
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2上下游产品信息
上游原料
下游产品
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2生产厂家
- 公司名称：SIGMA
- 联系电话：--
- 电子邮件：
- 国家：瑞士
- 产品数：6896
- 优势度：91
88377-68-8, TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2相关搜索:
