ChemicalBook CAS数据库列表 夫雷非班
夫雷非班
- CAS号:148396-36-5
- 英文名:Fradafiban
- 中文名:夫雷非班
- CBNumber:CB81117082
- 分子式:C20H21N3O4
- 分子量:367.403
- MOL File:148396-36-5.mol
夫雷非班化学性质
- 密度 :1.38±0.1 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 溶解度 :Soluble in DMSO
- 酸度系数(pKa) :4.29±0.10(Predicted)
夫雷非班性质、用途与生产工艺
- 生物活性 Fradafiban 是一种非肽血小板糖蛋白 IIb/IIIa 复合体拮抗剂，其与人血小板 GP IIb/IIIa 复合体结合，Kd 值为 148 nM。
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靶点
Kd: 148 nM (human platelet GP IIb/IIIa complex)
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体外研究
Fradafiban is a nonpeptide mimetic of the arginine-glycine-aspartic acid recognition sequence. Fradafiban binds with high affinity and selectivity to the human platelet GP IIb/IIIa complex and potently inhibits human platelet aggregation in vitro. Fradafiban reversibly binds to the human platelet GP IIb/IIIa complex with a K d value of 148 nM.
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体内研究
Fradafiban has only very limited oral activity probably due to its high polarity and thus poor absorption after oral ingestion.
夫雷非班上下游产品信息
上游原料
下游产品
夫雷非班生产厂家
- 公司名称：Leancare Ltd.
- 联系电话：--
- 电子邮件：enquiry@leancare.co.uk
- 国家：英国
- 产品数：6446
- 优势度：42
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