ChemicalBook CAS数据库列表 希美加群
希美加群
- CAS号:192939-46-1
- 英文名:EXANTA
- 中文名:希美加群
- CBNumber:CB7838374
- 分子式:C24H35N5O5
- 分子量:473.57
- MOL File:192939-46-1.mol
希美加群化学性质
- 熔点 :65-68?C
- 密度 :1.35±0.1 g/cm3(Predicted)
- 储存条件 :-20°C
- 溶解度 :DMSO : 250 mg/mL (527.91 mM; Need ultrasonic)Methanol : 62.5 mg/mL (131.98 mM; Need ultrasonic)
- 酸度系数(pKa) :6.87±0.69(Predicted)
- 形态 :powder
- 颜色 :white to beige
- 稳定性 :Hygroscopic
希美加群性质、用途与生产工艺
- 生物活性 Ximelagatran (H 376/95) 是一种口服活性凝血酶抑制剂，可选择性和竞争性地抑制游离和凝块结合的凝血酶。Ximelagatran 还是一种抗凝药物，具有快速起效的抗凝作用，可预测的，剂量依赖性的药代动力学和药效学。
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体外研究
Ximelagatran is an orally administered direct thrombin inhibitor under development as an anticoagulant agent for prophylaxis against and treatment of thromboembolism. Ximelagatran is rapidly absorbed and quickly converted into its active form Melagatran, a reversible, active-site inhibitor of both free and clot-bound thrombin that has stable and reproducible pharmacokinetic properties. Initial studies have shown Ximelagatran to have good efficacy and safety in the prevention of venous thromboembolism after total knee or total hip replacement.
希美加群上下游产品信息
上游原料
下游产品
希美加群生产厂家
- 公司名称：Leancare Ltd.
- 联系电话：--
- 电子邮件：enquiry@leancare.co.uk
- 国家：英国
- 产品数：6460
- 优势度：42
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