生物活性 靶点 体外研究
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ASP-SER-PHE-VAL-GLY-LEU-MET-NH2

ASP-SER-PHE-VAL-GLY-LEU-MET-NH2,97559-35-8,结构式
ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
  • CAS号:97559-35-8
  • 英文名:NEUROKININ A (4-10)
  • 中文名:ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
  • CBNumber:CB7396146
  • 分子式:C34H54N8O10S
  • 分子量:766.91
  • MOL File:97559-35-8.mol
ASP-SER-PHE-VAL-GLY-LEU-MET-NH2化学性质
  • 沸点 :1231.2±65.0 °C(Predicted)
  • 密度 :1.276±0.06 g/cm3(Predicted)
  • 储存条件 :−20°C
  • 溶解度 :Soluble in DMSO
  • 形态 :Solid
  • 酸度系数(pKa) :3.69±0.10(Predicted)
安全信息
  • WGK Germany :3

ASP-SER-PHE-VAL-GLY-LEU-MET-NH2性质、用途与生产工艺

  • 生物活性 Neurokinin A (4-10) 是速激肽 NK2 受体激动剂。
  • 靶点

    NK 2 receptor

  • 体外研究

    Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK 2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK 2 receptor in human colon circular muscle. A high density of NK 2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding.

ASP-SER-PHE-VAL-GLY-LEU-MET-NH2上下游产品信息
上游原料
下游产品
ASP-SER-PHE-VAL-GLY-LEU-MET-NH2生产厂家
  • 公司名称:SIGMA
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  • 国家:瑞士
  • 产品数:6913
  • 优势度:91