2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖

2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖化学性质

熔点 :137 - 140°C
沸点 :740.0±70.0 °C(Predicted)
密度 :1.750±0.06 g/cm3(Predicted)
储存条件 :Inert atmosphere,Store in freezer, under -20°C
溶解度 :Soluble in DMSO (up to 10 mg/ml).
形态 :solid
酸度系数(pKa) :12.96±0.20(Predicted)
颜色 :Dark yellow to orange/red
BRN :7603370
稳定性 :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

安全信息

2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖性质、用途与生产工艺

生物活性 2-NBDG，一种荧光脱氧葡萄糖衍生物，是检测葡萄糖摄取的标志物，也用于检测细胞活力。
体外研究

It has since been demonstrated in living mammalian cells that the uptake of 2-NBDG takes place through glucose transporters (GLUTs) in a concentration-, time- and temperature-dependent manner. A short-period application of 2-NBDG produced a remarkable increase in the fluorescence intensity in COS-1 cells over-expressing GLUT2, whereas the increase was barely detectable in mock-transfected cells. In mouse insulin-secreting clonal MIN6 cells, uptake was inhibited by cytochalasin B, a specific blocker for GLUTs, and by D-glucose in a dose-dependent manner.

2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖上下游产品信息

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下游产品

2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖生产厂家

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