ChemicalBook CAS数据库列表 N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide
N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide
![N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide,850467-66-2,结构式](https://www.chemicalbook.com/CAS/20180601/GIF/850467-66-2.gif)
- CAS号:850467-66-2
- 英文名:N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide
- 中文名:N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide
- CBNumber:CB73375744
- 分子式:C25H24N2O2
- 分子量:384.47
- MOL File:850467-66-2.mol
N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide化学性质
- 沸点 :673.2±54.0 °C(Predicted)
- 密度 :1.22±0.1 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 溶解度 :DMSO: 100 mM; Ethanol: 20 mM
- 形态 :A solid
- 酸度系数(pKa) :13.08±0.46(Predicted)
- 颜色 :White to off-white
N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide性质、用途与生产工艺
- 生物活性 TAO Kinase inhibitor 1 (compound 43) 是一种选择性的、ATP 竞争性的 thousand-and-one amino acid kinases (TAOK) 抑制剂，针对 TAOK1 和 TAOK2 的 IC50s 分别为 11 nM 和 15 nM。TAO Kinase inhibitor 1 延迟有丝分裂以及诱导有丝分裂细胞死亡。
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体外研究
TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death in centrosome amplified breast cancer cells.
N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide上下游产品信息
上游原料
下游产品
N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]biphenyl-4-carboxamide生产厂家
- 公司名称：TOCRIS-US
- 联系电话：--
- 电子邮件：customerservice@tocris.co.uk
- 国家：英国
- 产品数：5726
- 优势度：77
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