DBCO-(PEG2-VAL-CIT-PAB)2

生物活性靶点体外研究

DBCO-(PEG2-VAL-CIT-PAB)2性质、用途与生产工艺

生物活性 DBCO-(PEG2-Val-Cit-PAB)2 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。DBCO-(PEG2-Val-Cit-PAB)2 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。
靶点

Cleavable

Alkyl/ether

PEGs
体外研究

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

DBCO-(PEG2-VAL-CIT-PAB)2上下游产品信息

上游原料

下游产品

DBCO-(PEG2-VAL-CIT-PAB)2生产厂家