ANTI-CASPASE-3

ANTI-CASPASE-3化学性质

安全信息

ANTI-CASPASE-3性质、用途与生产工艺

描述 Anti-Caspase-3 antibody
宿主/亚型 Rabbit / IgG
种属反应性 Human
偶联物 Unconjugated
品牌示例
Thermofisher
Caspase 3 Antibody (PA5-14504) in IHC
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung carcinoma tissue using a Caspase-3 polyclonal antibody (Product # PA5-14504), followed by HRP-conjugated secondary antibody and DAB staining.
背景 This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

ANTI-CASPASE-3上下游产品信息

上游原料

下游产品

ANTI-CASPASE-3生产厂家