BETA-岚香酮酸

BETA-岚香酮酸化学性质

熔点 :224-225°C
沸点 :565.2±50.0 °C(Predicted)
密度 :1.07
储存条件 :2-8°C
溶解度 :DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
形态 :A crystalline solid
酸度系数(pKa) :4.65±0.10(Predicted)
颜色 :White to off-white

BETA-岚香酮酸性质、用途与生产工艺

生物活性 β-Elemonic acid 是从乳香树中分离得到的三萜。β-Elemonic acid 诱导细胞凋亡，活性氧 (ROS) 和 COX-2 表达，并抑制脯氨酰内肽酶。β-Elemonic acid 具有抗癌和抗炎作用。
靶点

COX-2
体外研究

β-elemonic acid (1, 3, 10, 20 µM; 24 hours) strongly induces human A549 lung cancer cell apoptosis in a dose- and time-dependent manner.
β-elemonic acid (1, 3, 10, 20 µM; 24 hours) exerts potent cytotoxic effects on human NSCLC A549 cells in a dose-dependent manner. The IC ₅₀ value following a 24-h exposure to β-elemonic acid was 6.92 µM.
β-elemonic acid (20 µM; 24 hours) results in a cell percentage of 58.01% in the G0/G1 phase.
β-elemonic acid (1, 3, 10, 20 µM; 24 hours) inhibits phosphorylation of p42/44, MAPK/JNK and p38 in the A549 cells.
化学性质白色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于乳香。

BETA-岚香酮酸上下游产品信息

上游原料

下游产品

BETA-岚香酮酸试剂级价格

BETA-岚香酮酸生产厂家

28282-25-9, BETA-岚香酮酸相关搜索: