ChemicalBook CAS数据库列表 糖尿病相关肽(胰岛淀粉样肽)(抗原)
糖尿病相关肽(胰岛淀粉样肽)(抗原)
- CAS号:122384-88-7
- 英文名:AMYLIN, HUMAN
- 中文名:糖尿病相关肽(胰岛淀粉样肽)(抗原)
- CBNumber:CB6710129
- 分子式:C8H17O3*
- 分子量:161.21878
- MOL File:122384-88-7.mol
糖尿病相关肽(胰岛淀粉样肽)(抗原)化学性质
- 储存条件 :-20°C
- 形态 :Solid
- 颜色 :White to off-white
- 水溶解性 :Soluble to 5 mg/ml in water and in 5% acetic acid.
安全信息
- WGK Germany :3
- 海关编码 :2937190000
糖尿病相关肽(胰岛淀粉样肽)(抗原)性质、用途与生产工艺
- 生物活性 Amylin, amide, human 是一种 37 个氨基酸的多肽,是一种与胰岛素共分泌的胰腺激素,在代谢和葡萄糖稳态中发挥独特作用。Amylin, amide, human 抑制胰高血糖素分泌,延迟胃排空,并作为饱腹感剂。
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体外研究
MCF-7 cells endogenously express human amylin receptor CTR1 and CTR2. Stimulation of the receptor with Amylin, amide, human results in the production of cAMP. Amylin, amide, human (0.001 nM-1000 μM) results in an EC 50 of 35.2±7.5 nM.
Cell Viability Assay
Cell Line: MCF-7 cells Concentration: 0.001 nM, 0.01 nM, 0.1 nM, 1 nM, 10 nM, 100 nM, 1 μM, 10μM, 100 μM, 1000 μM Incubation Time: Result: Resulted in the production of cAMP with an EC 50 of 35.2±7.5 nM. -
体内研究
Amylin, amide, human (400 μg peptide /kg body weight) is injected by subcutaneous route in separated groups of swiss male mice. A typical PK curve for the free amylin is observed, with a half-time of 23 min.
Animal Model: Swiss male mice (8 weeks old) Dosage: 400 μg peptide /kg body weight (Pharmacokinetic Analysis) Administration: Subcutaneous route; 24 hours Result: Half-time of 23 min.
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糖尿病相关肽(胰岛淀粉样肽)(抗原) 试剂级价格
- 更新日期:2024/11/08
- 产品编号:HY-P1070
- 产品名称:糖尿病相关肽(胰岛淀粉样肽)(抗原) Amylin, amide, human
- CAS编号:122384-88-7
- 包装:500μg
- 价格:2400元
- 更新日期:2024/11/08
- 产品编号:HY-P1070
- 产品名称:糖尿病相关肽(胰岛淀粉样肽)(抗原) Amylin, amide, human
- CAS编号:122384-88-7
- 包装:1mg
- 价格:3850元
糖尿病相关肽(胰岛淀粉样肽)(抗原)生产厂家
- 公司名称:SIGMA
- 联系电话:--
- 电子邮件:
- 国家:瑞士
- 产品数:6896
- 优势度:91
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