ChemicalBook CAS数据库列表 OXYTHIAMINE HYDROCHLORIDE
OXYTHIAMINE HYDROCHLORIDE
- CAS号:136-16-3
- 英文名:OXYTHIAMINE HYDROCHLORIDE
- 中文名:OXYTHIAMINE HYDROCHLORIDE
- CBNumber:CB6428626
- 分子式:C12H17Cl2N3O2S
- 分子量:338.25
- MOL File:136-16-3.mol
OXYTHIAMINE HYDROCHLORIDE化学性质
- 密度 :1.2416 (rough estimate)
- 折射率 :1.6740 (estimate)
- 储存条件 :−20°C
- 溶解度 :DMSO : 51.67 mg/mL (194.00 mM)
- 形态 :Solid
- 颜色 :White to off-white
安全信息
- WGK Germany :3
- RTECS号 :XJ7034100
- 毒性 :LD50 scu-mus: 1430 mg/kg PCJOAU16,848,82
OXYTHIAMINE HYDROCHLORIDE性质、用途与生产工艺
- 生物活性 Oxythiamine 是一种抗代谢物和维生素B1 (vitamin B1)拮抗剂，也是众所周知的硫铵 (thiamine) 拮抗剂和转酮醇酶 (transketolase) 抑制剂。
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靶点
Vitamin B1, Thiamine, Transketolase.
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体外研究
Oxythiamine, an antimetabolite and a vitamin B1 antagonist, is a well-known thiamine antagonist and inhibitor of transketolase. Oxythiamine alters protein expression in a dose dependent manner. The level of alpha-enolase is increased by Oxythiamine treatment, while expression of 14-3-3 protein beta/alpha is suppressed by Oxythiamine at a stratified dose. Oxythiamine causes dynamic changes of total protein expression in time dependent fashion. Oxythiamine suppresses expression of cellular phosphor proteins significantly.
OXYTHIAMINE HYDROCHLORIDE上下游产品信息
上游原料
下游产品
OXYTHIAMINE HYDROCHLORIDE 试剂级价格
- 更新日期：2025/02/08
- 产品编号：HY-107430
- 产品名称：Oxythiamine
- CAS编号：136-16-3
- 包装：5 mg
- 价格：218元
- 更新日期：2025/02/08
- 产品编号：HY-107430
- 产品名称：Oxythiamine
- CAS编号：136-16-3
- 包装：10 mg
- 价格：350元
OXYTHIAMINE HYDROCHLORIDE生产厂家
- 公司名称：SIGMA
- 联系电话：--
- 电子邮件：
- 国家：瑞士
- 产品数：6896
- 优势度：91
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