生物活性 靶点 体外研究 体内研究 BETA-AMYLOID (1-28) 试剂级价格
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BETA-AMYLOID (1-28)

BETA-AMYLOID (1-28),109770-29-8,结构式
BETA-AMYLOID (1-28)
  • CAS号:109770-29-8
  • 英文名:H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH
  • 中文名:BETA-AMYLOID (1-28)
  • CBNumber:CB6344029
  • 分子式:C145H209N41O46
  • 分子量:3262.46
  • MOL File:109770-29-8.mol
BETA-AMYLOID (1-28)化学性质
  • 密度 :1.52±0.1 g/cm3(Predicted)
  • 储存条件 :−20°C
  • 溶解度 :Soluble in DMSO
  • 形态 :White lyophilized powder.
  • 序列 :H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH
安全信息
  • WGK Germany :3

BETA-AMYLOID (1-28)性质、用途与生产工艺

  • 生物活性 β-Amyloid (1-28) 是可参与金属结合的β-淀粉样蛋白片段。β-淀粉样蛋白是在阿尔茨海默病患者的脑中形成淀粉样斑块的肽。
  • 靶点

    Amyloid-β

  • 体外研究

    β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
    1. Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure.
    2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃.
    3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing.
    4. Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments.

  • 体内研究

    β-Amyloid (1-28) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu 2+ interaction. Copper binds to β-Amyloid (1-28) at pH 7.4 with an affinity of K a 10 7 M -1 .

  • 参考质量标准 外观:白色粉末
    纯度(HPLC) ≥98.0%
    醋酸根含量5.0%~12.0%
    水分含量≤8.0%
    肽含量≥80.0%
BETA-AMYLOID (1-28)上下游产品信息
上游原料
下游产品
BETA-AMYLOID (1-28) 试剂级价格
  • 更新日期:2023/03/20
  • 产品编号:HY-P1468
  • 产品名称:BETA-AMYLOID (1-28) β-Amyloid (1-28)
  • CAS编号:109770-29-8
  • 包装:1mg
  • 价格:1600元
  • 更新日期:2023/03/20
  • 产品编号:HY-P1468
  • 产品名称:BETA-AMYLOID (1-28) β-Amyloid (1-28)
  • CAS编号:109770-29-8
  • 包装:5mg
  • 价格:6400元
BETA-AMYLOID (1-28)生产厂家
  • 公司名称:吉尔生化(上海)有限公司
  • 联系电话:21-61263452 13641803416
  • 电子邮件:ymbetter@glbiochem.com
  • 国家:中国
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  • 公司名称:雷丁试剂
  • 联系电话:0510-85629785 18013409632
  • 电子邮件:sales@reading-chemicals.com
  • 国家:中国
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  • 公司名称:上海超岚化工科技中心
  • 联系电话:021-QQ:65489617 15618227136
  • 电子邮件:Sales@ATKchemical.com
  • 国家:中国
  • 产品数:7296
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  • 公司名称:南京肽业生物科技有限公司
  • 联系电话:025-025-58361106-805-805 13082558573
  • 电子邮件:liugang@njpeptide.com
  • 国家:中国
  • 产品数:9980
  • 优势度:55
  • 公司名称:成都云希化工有限公司
  • 联系电话:+86-17380623303 +86-17380623303
  • 电子邮件:Caroline@youngshechem.com
  • 国家:中国
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