(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)

(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)化学性质

(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)性质、用途与生产工艺

生物活性 (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 是一种有效的竞争性甲状旁腺激素 (PTH) 拮抗剂，在牛肾皮质膜中的 Ki 值为 69 nM。(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 可用于生长发育调节。
靶点

Ki: 69 nM (PTH)
体外研究

(D-Trp12,Tyr34)-pTH (7-34) amide (0.05-10 μM) causes a concentration-dependent inhibition of PTHrP or PTH-stimulated cAMP formation in opossum kidney (OK) cells.
(D-Trp12,Tyr34)-pTH (7-34) amide (0.1-10 μM) attenuates inhibition of Nap _i T promoted by 1 nM of either PTHrP or PTH.
体内研究

(D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung.

(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)上下游产品信息

上游原料

下游产品

更新日期：2024/11/08
产品编号：HY-P2426
产品名称：(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) (D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
CAS编号：118102-98-0
包装：1mg
价格：720元

更新日期：2024/11/08
产品编号：HY-P2426
产品名称：(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) (D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
CAS编号：118102-98-0
包装：5mg
价格：1800元

(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)生产厂家

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