BIS-PEG21-NHS ESTER;≥98%

生物活性靶点体外研究

BIS-PEG21-NHS ESTER;≥98%化学性质

BIS-PEG21-NHS ESTER;≥98%性质、用途与生产工艺

生物活性 Bis-PEG21-NHS ester 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。Bis-PEG21-NHS ester 可用于合成一系列 PROTAC 分子。Bis-PEG21-NHS ester 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
靶点

PEGs

Alkyl/ether

Cleavable
体外研究

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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BIS-PEG21-NHS ESTER;≥98%生产厂家