描述 宿主 种属反应性 免疫原 偶联性 验证的应用 制备 品牌示例 背景
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ANTI-CD28抗体

ANTI-CD28抗体,,结构式
ANTI-CD28抗体
  • CAS号:
  • 英文名:Anti-CD28 Antibody
  • 中文名:ANTI-CD28抗体
  • CBNumber:CB55712444
  • 分子式:
  • 分子量:0
  • MOL File:Mol file

ANTI-CD28抗体性质、用途与生产工艺

  • 描述

    小鼠单克隆抗体to CD28

  • 宿主 Mouse
  • 种属反应性

    与反应: Human

  • 免疫原 Stimulated human leucocytes.
  • 偶联性

    Unconjugated

  • 验证的应用

    适用于: Flow Cyt, IHC-Fr

  • 制备

    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD28 (rh CD28; Catalog#11524-H08H; P10747-1; Met 1-Pro 152). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

  • 品牌示例

    Immunocytochemistry/ Immunofluorescence - Anti-CD28 antibody [CB28] (ab193350)

    ab193350

    Immunofluorescent staining of Jurkat cells using ab193350 followed by goat anti-Mouse IgG conjugated to CF488 (green). Red Dot is used to label nuclei (red).

  • 背景

    CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

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