ChemicalBook CAS数据库列表 Α-突刺蛋白61-75
Α-突刺蛋白61-75
- CAS号:440645-08-9
- 英文名:L-Threonine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-
- 中文名:Α-突刺蛋白61-75
- CBNumber:CB48382669
- 分子式:C60H103N17O23
- 分子量:1430.58
- MOL File:440645-08-9.mol
Α-突刺蛋白61-75化学性质
- 沸点 :1886.8±65.0 °C(Predicted)
- 密度 :1.304±0.06 g/cm3(Predicted)
- 酸度系数(pKa) :3.23±0.10(Predicted)
Α-突刺蛋白61-75性质、用途与生产工艺
- 生物活性 α-Synuclein (61-75) 是 α-Synuclein 的 61-75 片段。α-Synuclein 是一种丰富的神经元蛋白，在突触前神经末梢高度丰富。α-Synuclein 是一种帕金森氏病 (PD) 的生物标志物。
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体外研究
Lewy bodies containing α-Synuclein are a neuropathological hallmark of PD, and missense mutations in α-Synuclein (A30P, E46K, H50Q, G51D, A53E, A53T), as well as α-Synuclein gene duplications and triplications, appear to cause PD. Moreover, polymorphisms in regulatory elements of the α-Synuclein gene predispose individuals to PD and are linked to an early onset of the disease. The non-Aβ-amyloid component (NAC) region of α-synuclein is relatively hydrophobic and aggregation-prone in human α-Synuclein but not in mouse α-Synuclein nor in the corresponding homologous region of human β-synuclein. Yet, β-synuclein is more homologous to α-synuclein in the N-terminal sequences (74%) than γ-synuclein (67%).
Α-突刺蛋白61-75上下游产品信息
上游原料
下游产品
Α-突刺蛋白61-75生产厂家
- 公司名称：MedChemExpress
- 联系电话：--
- 电子邮件：sales@medchemexpress.com
- 国家：美国
- 产品数：6398
- 优势度：58
